Not really no, as the boiler won't be able to modulate down enough to achieve that lower temperature and stay there. Of course this will happen if you've only got demand on a few radiators, if your full system is calling for heat then your boiler will modulate accordingly.
You've jumped from TPI on an old non-modulating boiler to Opentherm on a boiler that modulates - yes I'd expect you'd see some gain in comfort levels as your old boiler would have just cycled rather than modulated. I suspect if you used TPI on your new boiler you wouldn't notice much difference if any in comfort levels - throw in the fact that Evohome requests 100% heat demand from any zone 1.5oc of the set point you could actually argue that other zones requesting small amounts of heat might actually overshoot.
I'm actually running an old non condensing non modulating boiler with TPI and don't experience any issues with comfort levels or overshoots - apart from when the system is relearning (Had an issue with a TRV playing up that'd i'd corrected).